ABSTRACT

Drugdevelopment is alengthy, high-risk, and costly process, which usually spans 10-15 years following the established paradigms.1 Drug companies currently have hundreds of thousands of potential drug compounds; however, using traditional discovery and development methods, less than 1of every 10,000 will eventually enter the market as an FDA-approved treatment. The timeline and success rate of drug development can be improved by the use of highly speci‹c target related

CONTENTS

Introduction .................................................................................................................................... 895 Multimodality Imaging Techniques ..............................................................................................897