This research work focuses on process characteristics of polymer solutions, such as viscosity and electrical conductivity, as well as the parameters of electrospinning using poly 3-hydroxybutyrate modified by titanium dioxide nanoparticles, which have been optimized. Both physical-mechanical characteristics and photooxidation stability of materials have been improved. The structure of materials has been examined by means of X-ray diffraction, differential scanning calorimetry (DSC), IRspectroscopy, and physical-mechanical testing. The fibrous materials obtained can find a wide application in medicine and filtration techniques as scaffolds for cell growth, filters for body fluids and gas-air media, and sorbents.