ABSTRACT

Examination reveals mild glandular gynecomastia, according to the Simon classification, with no evidence of testicular abnormality or axillary lymphadenopathy. He takes nifedipine and aspirin and no other medications. His older sister had a mastectomy for right-sided breast cancer at age 70 and continues to do well. Which one of the following statements is correct regarding the patient? A. His risk of developing breast cancer is typically one twentieth that of his sister. B. None of his medications are likely to account for gynecomastia. C. His age is the most common age for a diagnosis of male breast cancer. D. Mammography is the best clinical investigation to exclude malignancy. E. His risk of malignancy is unaffected by his sister’s previous disease.