ABSTRACT
By 1980, 423 dierent natural compounds had been identied in Cannabis sativa L. (Turner et al., 1980). By 1995, the number had risen to 483, and more recently, six new compounds, four cannabinoids and two avonoids, have been described (Ross et al., 2005). Some of these components (e.g., cannabinoids such as cannabidiol [CBD]) appear to be neuroprotective, in spite of numerous reports describing psychosis in cannabis users (Howes and Perry, 2011). e major psychoactive constituent of marijuana is Δ9-tetrahydrocannabinol (THC). THC may be synthesized using citral and olivetol in boron triuoride and methylene chloride (Lander et al., 1976).
