ABSTRACT
Before going into detail concerning the generation of radial tethering forces at rest, it should be recalled that Hill (1968a) deduced from his experimental results, obtained with whole frog muscles (at low temperature), that ‘in a resting muscle, the crossbridges on the myosin filaments are not entirely inactive, but a very small proportion of them are cross-linked with the actin filaments’. This inference regarding the existence of ‘resting’ attached cross-bridges has been largely ignored but was later confirmed by several independent groups (see below, in this section).
