ABSTRACT

Abnormal serum concentrations of hepatic enzymes (‘liver function tests’, Table 6.1) are a common finding that may be due to any systemic viral illness, or may reflect more serious pathology, including metastases or chronic liver disease. They may be detected while investigating patients with non-specific symptoms, as an incidental finding in blood donors, or during a routine check-up. Overt jaundice can be considered as part of the spectrum of abnormal liver function tests, necessitating expeditious investigation.