ABSTRACT

In countries where CHD is prevalent, preventive strategies must aim,

on the one hand, to diminish the average level of risk in the general

population and, on the other, to target for more intensive intervention

those people who already have clinical CHD or are likely to acquire it

in the near future. The latter is the ‘high-risk’ or clinical approach for

which clinical trial evidence is strong. It is obviously a better option for

individuals at high-risk than reliance on population strategies.