ABSTRACT
Routine screening tests are carried out in most pregnancies in the UK, and further tests are available for those at higher risk of a fetal abnormality. Recent advances in antenatal imaging and DNA techniques have widened the range of conditions which can be diagnosed antenatally. Accurate prenatal diagnosis has allowed the advancement of in vitro treatment for certain conditions, e.g. rhesus disease and some congenital renal and lung abnormalities. It is also allows delivery of the baby in a centre with facilities for intensive care and neonatal surgery. In severe disorders for which no treatment is available, termination of pregnancy may be indicated, so the parents must be counselled carefully and find this acceptable before extensive investigations are instituted.
