ABSTRACT
Studies suggest that between 60 and 70% of migraineurs experience an improvement in their migraine during pregnancy, particularly during the second and third trimesters. The mechanism is often considered to be the more stable levels of oestrogen during pregnancy. However, it is unlikely that the true mechanism is so simple as there are many physical, biochemical, and emotional changes in pregnancy which could account for improvement, including increased production of endorphins, muscle relaxation, and altered glucose tolerance.
