ABSTRACT
Despite major gaps in our knowledge of the pathogenesis, epidemiology and genetics of multiple sclerosis, much progress has been made, not only in those areas of research, but also in refining confirmatory laboratory diagnostic procedures and improving methods of symptomatic treatment. Therapeutic trials for long-term treatment have shown encouraging results, but as yet unproved results over the long term. What remains unchallenged is the primary role played by the astute and experienced clinician in the diagnosis and treatment of the disease.
