ABSTRACT

Variable degrees of dermal fibrosis and chronic inflammation are present in the papillary and upper reticular dermis. Focal vascular and tissue necrosis may be present along with an associated chronic inflammatory infiltrate. Fat necrosis is often found, associated with an infiltrate of foamy macrophages and mononuclear cells (Figure 12.6). Inflammation is mild relative to the degree of

apparent tissue damage. The inflammation does not seem to be centered around hair follicles, but is usually associated with foci of vascular and tissue necrosis.