ABSTRACT
Two of the three dominant pathologies affecting the prostate gland, namely, benign prostatic hyperplasia and prostate cancer, are characterized by excessive cell proliferation. In contrast, prostatitis is predominantly an inflammatory disorder. In benign prostatic hyperplasia, the benign proliferative process affects both epithelial and stromal cells of the transitional zone. In contrast, prostate cancer is found more commonly in the peripheral zone, where it arises from atypical luminal cells or their stem cells.
