ABSTRACT

Quinazil Indications: Hypertension Category: Angiotensin-converting enzyme (ACE) inhibitor; Antihypertensive Half-life: 1-2 hours Clinically important, potentially hazardous interactions with: amiloride,

spironolactone, triamterene

Reactions

Skin Angioedema (<1%)

(2001): Cohen EG+, Ann Otol Rhinol Laryngol 110(8), 701 (64 cases) (1997): Sigler C+, Arch Dermatol 113, 972 (1996): Boxer M, J Allergy Clin Immunol 98, 471 (1995): Maier C, Anaesthesist (German) 44, 875 (1994): Cosano L+, Med Clin (Barc) (Spanish) 102, 275 (1993): Mendez-Mora JL+, Med Clin (Barc) (Spanish) 101, 76 (1992): Materson BJ, Am J Cardiol 69, 46C (1989): Sedman AJ+, Angiology 40(4 Pt 2), 360 Ankle edema (1992): Bahena JH+, Clin Ther 14, 527 Bullous eruption (1998): Sienkiewicz G, Johnson City, NY (from Internet) (observation) Diaphoresis (<1%) (1991): Morant J+, Arzneimittel-Kompendium der Schweiz (German) Basel, Documed, 1990 (1989): Frank GJ+, Angiology 40(4 Pt 2), 405 (1989): Maclean D, Angiology 40(4 Pt 2), 370 Edema (1989): Frank GJ+, Angiology 40(4 Pt 2), 405 (1989): Frank GJ, Cardiology 76(Suppl 2), 56 Exanthems (1991): Morant J+, Arzneimittel-Kompendium der Schweiz (German) Basel, Documed,

1990 Exfoliative dermatitis (<1%) Facial edema (sic)

(1989): Sedman AJ+, Angiology 40(4 Pt 2), 360 Flushing (<1%) Pemphigus (<1%) Pemphigus foliaceus (2000): Ong CS+, Australas J Dermatol 41(4), 242 Pemphigus vulgaris (2000): Ong CS+, Australas J Dermatol 41(4), 242 Peripheral edema (<1%) (1991): Wadworth AN+, Drugs 41, 378 Photosensitivity (<1%) (1989): Maclean D, Angiology 40(4 Pt 2), 370 Pruritus (<1%) (1991): Cetnarowski-Cropp AB, Drug Intell Clin Pharm 25, 499 (1991): Morant J+, Arzneimittel-Kompendium der Schweiz (German) Basel, Documed,

1990 (1990): Frishman WH, Clin Cardiol 13(Suppl 7), VII 19 (1990): Swartz RD+, J Clin Pharmacol 30, 1136 (1989): Frank GJ+, Angiology 40(4 Pt 2), 405 (1989): Frank GJ, Cardiology 76(Suppl 2), 56 (1989): Maclean D, Angiology 40(4 Pt 2), 370 Rash (sic) (1.2%) (1992): Materson BJ, Am J Cardiol 69, 46C (1989): Frank GJ+, Angiology 40(4 Pt 2), 405 (1989): Frank GJ, Cardiology 76(Suppl 2), 56 (1989): Maclean D, Angiology 40(4 Pt 2), 370 (1989): Taylor SH, Angiology 40 (4 Pt 2), 382 Urticaria (<1%) Vasculitis (<1%)

Hair Hair-alopecia (<1%)

Other Cough

(2002): Culy CR+, Drugs 62(2), 339 (2-4%) (2001): Adigun AQ+, West Afr J Med 20(1), 46-7 (2001): Lee SC+, Hypertension 38(2), 166 Dysgeusia (1991): Cetnarowski-Cropp AB, Drug Intell Clin Pharm 25, 499 (1989): Taylor SH, Angiology 40(4 Pt 2), 382 Headache Hypersensitivity Myalgia (1.5%) Paresthesias (<1%) Xerostomia (<1%)