ABSTRACT

Rash (sic) (<1%) Sarcoidosis (1986): Yamada S+, J Dermatol (Tokio) 13, 217 Stevens-Johnson syndrome (1994): Wong SS, Acta Derm Venereol 74, 475 Toxic epidermal necrolysis Urticaria (<1%) Vesiculobullous eruption (1977): Heid E+, Ann Dermatol Venereol (French) 104, 494 Xerosis

Hair Hair-alopecia (<1%)

(1971): Five Year Study, BMJ 4, 767 (0.8%) Hair-dry (<1%)

Other Dysgeusia

Gynecomastia Hypogeusia Myalgia Myopathy (<1%) (1976): Rumpf KW+, Lancet 1, 249 (1975): Pierides AM+, Lancet 2, 1279 (1968): Langer T+, N Engl J Med 279, 856 Oral ulceration (1973): Howard EJ+, JAMA 226, 1358 Rhabdomyolysis (1977): Smals AG+, N Engl J Med 296(16), 942 Stomatitis

Trade names: Clomid (Aventis); Serophene (Serono) Other common trade names: Clom 50; Clomifen; Dyneric; Milophene; Omifin;

Pergotime; Phenate; Serophene Indications: Ovulatory failure Category: Infertility therapy adjunct; Ovulation stimulator Half-life: 5-7 days

Reactions

Skin Acne

(2001): Guzick ND, Houston, TX (from Internet) (several observations) Allergic reactions (sic) Dermatitis (sic) (<1%) Diaphoresis Edema Erythema Erythema multiforme Erythema nodosum (1980): Salvatore MA+, Arch Dermatol 116, 557 Exanthems (1996): Coots NV+, Cutis 57, 91 (1966): Johnson JE+, Pacif Med Surg 74, 153 (0.8%) Flushing (10%) (1966): Johnson JE+, Pacif Med Surg 74, 153 (14%) Hot flashes (>10%) Melanoma (1999): Fuller PN, Am J Obstet Gynecol 180, 1499 (1995): Rossing MA+, Melanoma Res 5, 123 (1992): Kuppens E+, Melanoma Res 2, 71 Pruritus Purpura (palpable) (1996): Coots NV+, Cutis 57, 91 Rash (sic) (<1%) Urticaria (1969): Drug and Therapeutic Bulletin (London) 7, 34

Hair Hair-alopecia (<1%)

(1969): Drug and Therapeutic Bulletin (London) 7, 34 (0.4%) (1966): Johnson JE+, Pacif Med Surg 74, 153 (0.3%) Hair-hypertrichosis (2001): Smith KC, Niagara Falls, ON, Canada (from Internet) (several observations)

Other Gynecomastia (1-10%)

(1978): Check JH+, Fertility and Sterility 30, 713 Headache Mastodynia (1-10%) Myalgia