ABSTRACT

A 34-year-old man, originally from India, first presented with a 6-month history of excessive thirst and polyuria. Over this period he had also noticed loss of libido and the appearance of skin lesions in his armpits. His symptoms were investigated but results were inconclusive and no definitive diagno­ sis was made. A year later he was admitted acutely with malaise, vomiting and severe thirst. Biochemical investigation showed hyperosmolar, non-ketotic diabetes mellitus, which was treated with insulin and fluid replacement. In spite of correction of the hyperglycaemia, the patient's thirst and

polyuria persisted. In addition, it was noted that the cutaneous eruption had extended. A dermatology opinion was requested.