ABSTRACT
Cutaneous manifestations ● Thick, yellow-brown, parchment-like hyperkeratosis involving palms and soles, well
demarcated by an erythematous ring (non-transgrediens form resembling Unna-Thost disease) (Figures 7.1-7.3)
● Decreased resistance to physical trauma resulting in blisters and erosions ● Hyperhidrosis
Course
There is a stable course, with difficulty in walking and social discomfort.