ABSTRACT
Pseudomembranous colitis (PMC) is commonly associated with hospitalization and prior
antibiotic exposure. PMC is currently believed to be caused almost exclusively by toxins
produced by Clostridium difficile. The clinical spectrum of this disease may range from a mild,
nonspecific diarrhea to severe colitis with toxic megacolon, perforation, and death (1).
Discontinuation of antibiotics and supportive therapy usually lead to resolution of this
disorder (2). PMC may affect all age groups, although a lower incidence was noted in
children (3).
