ABSTRACT

Laws and regulations are usually effected in order to protect an interest. The interests of individuals, institutions, society, and laboratory animals are protected by legislation and regulation. Examples in the United States (U.S.) include: the Occupational Safety and Health Act; the Good Laboratory Practices Act; and the Animal Welfare Act. Both U.S. and international regulations of interest to toxicologists have been recently reviewed (Merrill, 2003; Gad, 2007b). Such regulations are often promulgated in response to outrage over real or perceived irresponsible behavior.