ABSTRACT
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It cannot be denied that the ability to noninvasively derive structural, functional, metabolic, and
meanwhile also cellular and targeted information at high resolution, renders MR highly relevant for
pharmacological studies. Nevertheless, because the establishment and operation of an imaging
facility is costly, it is essential to address issues concerning the relevance of imaging contributions
for decision making. It is fundamental that questions such as “Could similar information be
generated more economically and/or more efficiently using other methods, like established
pharmacological techniques or ‘-omics’ technologies?” or “What is the added value of
sophisticated imaging procedures?” be addressed when MR methods are being considered for
use in drug research.
