ABSTRACT
T he main aim of imaging investigation is to identify the abnormal anatomy resulting from disease, so in the management of patients with diffuse liver disease imaging in general, and MRI in particular, has only a secondary role. With most forms of diffuse
hepatic disorder, diagnosis is primarily based on thorough clinical assessment along with tests of liver function and immunologic screening, often supplemented by percutaneous needle biopsy of the liver. Imaging is required for the investigation of associated vascular abnormalities, particularly portal hypertension and obstructions or occlusions of hepatic veins or parts of the portal venous system. Imaging is also needed to seek evidence of other complications including local hemorrhage or infection, iron deposition, and malignant change. Finally, imaging is needed to assess the anatomic suitability of patients for liver resection or transplantation.
