A Brief History of Migraine . . . . . . . . . . . . . . . . . . . . . . . . ‘‘Migraine’’—The Etymology of a 1

Migraine has fascinated physicians and scientists throughout the ages. The early literature abounds with the personal observations and insights of some of the most distinguished figures of the times. Although headache is the most prominent feature, the syndrome encompasses many other neurological phenomena that are encountered frequently in clinical practice. Yet it has no ‘‘pathological signature.’’ Even today, it is defined and recognized entirely by clinical history.