ABSTRACT

Material CAS No. Suggested Concentrations Category

Sodium lauryl sulfate 151-21-3 1.0% Irritant Hexyl cinnamic aldehyde

101-86-0 — Mild to moderate sensitizer

Mercaptobenzothiazole 149-30-4 — Mild to moderate sensitizer

Benzocaine 94-09-7 — Mild to moderate sensitizer

p-Phenylenediamine 106-50-3 — Sensitizer 2,4-Dinitrochlrobenzene (DNCB)

97-00-7 Induction: 0.1% to 0.5%, 0.25% w/v in ethanol/ acetone

Challenge: 0.1% to 0.3%, w/v in ethanol/acetone

Sensitizer

Potassium dichromate 7778-50-9 — Sensitizer Neomycin sulfate 1405-10-3 — Sensitizer Nickel sulfate 7786-81-4 — Sensitizer 8-Methoxypsoralen (Oxsoralen lotion©)

298-81-7 1.0% Photoirritant

Table 52  Relative Ranking of Skin Permeability in Different  Animal Species

Mouse > Guinea Pig > Rabbit > Dog > Monkey > Pig > Human > Chimpanzee Most permeable  Least permeable  

Source: Leung, H-W. and Paustenbach, D.J. (1999).