ABSTRACT
Extensions of the Standard Template demonstrate the flexibility of the Dynamic Modeling approach, as they allow for the structure that addresses some of the complexities of individual disease marketplaces. In some chronic indications, initial epidemiology data show a large Undiagnosed Patient population. Expanding the Standard Template structure to examine the stages or steps a patient must go through to receive a correct diagnosis may be of strategic importance. The symptoms of the condition are usually ignored or misinterpreted, resulting in a very low diagnosis rate. The detail of the Dynamic Modeling structure allows the various stages and times associated with the stock of Undiagnosed Patients to be identified and quantified. Patients actually suffering from mononucleosis, for example, are often misdiagnosed as having depression or chronic fatigue syndrome. Indications exhibiting high rates of misdiagnosis are often subject to epidemiology errors, as estimating how many patients are Misdiagnosed and the dynamics surrounding them is a difficult proposition.
