ABSTRACT
Conditions with * denotes calcification Acrobatic ears B J Plast Surg 42:719-721, 1989 Acromegaly* Actinic damage* JAAD 51:799-800, 2004 Addison’s disease – calcification/ossification of the auricular cartilage* Int J Derm 17:799-801, 1978; JAAD 19:1, 1988 Alopecia mucinosa Atopic dermatitis – lichenification with fibrosis Auricular prosthesis Bazex syndrome Cauliflower ear – nodular deformity with fibrosis Rook p.3018, 1998, Sixth Edition Chondromalacia – systemic chondromalacia (Meyenburg’s disease)* Cutaneous calcinosis* Laryngoscope 95:566-576, 1985; actinic damage, acromegaly, adrenal insufficiency, mechanical trauma, radiation therapy, diabetes mellitus, following frostbite, hypopituitarism, hypothyroidism, insect bites, chondritis, ochronosis, perichondritis, sarcoid, syphilitic perichondritis, hypertension, alkaptonuria, chondromalacia, familial cold hypersensitivity JAAD 51:799-800, 2004; JAAD 49:142-144, 2003 Diabetes mellitus* Diastrophic dysplasia – cystic ear during hemorrhagic phase; calcifies* J Bone Jt Surg 50A:113-118, 1968 Epidermolysis bullosa acquisita – ossification Exostoses Laryngoscope 95:566-576, 1985 Familial cold hypersensitivity* Fibrosis due to physical trauma with resolution of hematoma Rook p.3018, 1998, Sixth Edition Frostbite – vesicles, bullae, ischemic necrosis; calcification* Rook p.3021, 1998, Sixth Edition Gout* Hypopituitarism* J Clin Endocrinol Metab 55:354-357, 1982 Hypothyroidism* JAAD 51:799-800, 2004 Hyperthyroidism* Idiopathic Juvenile hyaline fibromatosis (infantile systemic hyalinosis) – nodular perianal lesions, ears, lips, gingival hypertrophy, hyperpigmentation, flexion contractures of joints, osteolytic defects, stunted growth Dermatology 190:148-151, 1995; Ped Derm 11:52-60, 1994 Keutel syndrome – unusual facies, brachytelephalangy, pulmonary stenosis* Am J Med Genet 24:289-294, 1986 Leprosy Lichen myxedematosus; scleromyxedema Lobomycosis Lyme disease Lymphoma, leukemia Nance-Sweeney chondrodysplasia* Birth Defects 6:25-27, 1970 Ochronosis* Ossification – auricular ossificans (ectopic ossification of the auricle) JAAD 49:142-144, 2003; Australas J Dermatol 39:268-270, 1998; Laryngoscope 95:566-576, 1985; secondary to frostbite; Addison’s disease South Med J 59:1268-1270, 1966 Perichondral fibrosis
Polyarteritis nodosa Pretibial myxedema AD 122:85, 1986 Pseudohypoparathyroidism Pseudopseudohypoparathyroidism Radiation therapy* Relapsing polychondritis Sarcoid* Scleroderma Scleromyxedema JAAD 44:273-281, 2001; Rook p.2626-2617, 1998, Sixth Edition; JAAD 33:37-43, 1995 Trauma – cauliflower ear; wrestler’s ear*
Allergic contact dermatitis – nickel, gold, palladium, hearing aids, ear drops, occupational contact dermatitis to headphones Contact Dermatitis 42:164, 2000; benign lymphoplasia (lymphocytoma cutis) (red-brown papules and nodules) of the earlobes induced by gold earrings JAAD 27:457-458, 1992; JAAD 16:83-88, 1987; contact urticaria Angioedema Bullous pemphigoid Rook p.3028, 1998, Sixth Edition Dermatitis herpetiformis Rook p.3028, 1998, Sixth Edition Hyper-IgE syndrome – retroauricular fissures AD 140:1119-1125, 2004 Linear IgA disease (chronic bullous disease of childhood) – perioral, eyelids, ears, scalp, perineum, vulva; annular polycyclic bullae Ped Derm 15:108-111, 1998 Lupus erythematosus – systemic lupus, subacute cutaneous LE, discoid lupus erythematosus Rook p.2444-2449, 1998, Sixth Edition; NEJM 269:1155-1161, 1963; chilblain lupus BJD 98:497-506, 1978; verrucous plaque Pemphigus foliaceus Pemphigus vegetans – verrucous plaque Rheumatoid nodule – intact or ulcerated Rook p.2566, 1998, Sixth Edition; JAAD 8:439-457, 1983; NEJM 277:7-9, 1967 Scleroderma – pallor and telangiectasia of external auditory canal Rook p.3029, 1998, Sixth Edition Urticaria
Accessory tragus – ear papule – isolated, Treacher Collins syndrome (mandibulofacial dysostosis; autosomal dominant); Goldenhaar syndrome ((oculo-auriculo-vertebral syndrome) – macroglossia, preauricular tags, abnormal pinnae, facial asymmetry, macrostomia, epibulbar dermoids, facial weakness, central nervous system, renal, and skeletal anomalies); Nagers syndrome; Wolf-Hirschhorn syndrome (chromosome 4 deletion syndrome), oculocerebrocutaneous syndrome Ped Derm 17:391-394, 2000; Townes-Brocks syndrome Am J Med Genet 18:147-152, 1984; VACTERL syndrome J Pediatr 93:270-273, 1978 Accessory lobule Congenital calcinosis cutis of the ear Cutis 75:90-91, 2005; JAAD 49:117-119, 2003
Congenital hypertrichosis lanuginosa – deformities of the external ear Rook p.2890-2891, 1998, Sixth Edition; J Genet Humaine 17:10-13, 1969 Congenital postauricular swelling – cyst of first branchial cleft Ped Derm 19:246-249, 2002 Giant antitragi Hypertrichosis of pinnae – infants of diabetic mothers Pediatrics 68:745-746, 1981
Diastrophic dysplasia – cystic masses of ears Elastotic nodules of the ears JAAD 50:100, 2004; Cutis 44:452-454, 1989 Primary open-angle glaucoma – diagonal earlobe creases J R Coll Physicians Lond 26:459-460, 1992 Weathering nodules – white papules along the helix BJD 135:550-554, 1996
Bromoderma – verrucous plaque Corticosteroids, topical – milia on pinna Clin Exp Derm Sep2 (3):285-286, 1977 Cyclosporine-induced folliculodystrophy – cobblestoned follicular papules JAAD 50:310-315, 2004 Dilantin – hypertrophy of retro-auricular folds Cutis 30:207-209, 1982 Diltiazem – photolichenoid drug eruption Iododerma – verrucous plaque Olanzapine – eruptive xanthomas AD 139:1045-1048, 2003 Retinoids – retinoid embryopathy – low-set ears JAAD 46:161-183, 2002; systemic retinoids – increased skin fragility of ears Thalidomide embryopathy – small malformed ears Rook p.3015-3016, 1998, Sixth Edition; Syndromes of the Head and Neck, 1990; p.29
