ABSTRACT

Infertility is also common, affecting about 15% of couples.2 The causes of infertility are multiple and diverse yet some, for example endometriosis and the polycystic ovary syndrome (PCOS) may also affect successful implantation and pregnancy outcome. With the development of assisted conception it is now possible to overcome or circumvent many of the problems presented by the subfertile couple. The main questions arising from the various therapies available are: do they increase the rate of miscarriage or fetal malformations? And if they are found to do so, is this caused by the treatment or is it a reflection of the underlying fertility disorder?