ABSTRACT

Introduction Life expectancy has increased impressively over the past century; this has naturally resulted in an increase in the number of older patients. NonHodgkin lymphoma is especially relevant in the elderly patient population as the median age of patients with this disorder is 65 years. All lymphoma subtypes are observed in this population, with some modest differences compared with those encountered in younger patients. Most of the large epidemiologic studies have found that elderly patients have a higher percentage of patients with aggressive lymphomas (diffuse large B-cell lymphoma, peripheral T-cell and less frequently anaplastic large cell lymphoma, Burkitt’s lymphomas). No specific chromosomal or genetic features have been described in elderly patients.