ABSTRACT
Synonyms: diphenylhydantoin; DPH; phenytoin sodium Trade names: Di-Hydran; Dilantin (Pfizer); Diphenylan; Epanutin; Fenytoin; Phenhydan; Phenytek; Pyoredol; Zentropil Indications: Grand mal seizures Category: Antiarrhythmic class Ib; Antiepileptic, hydantoin Half-life: 7-42 hours (dose dependent) Clinically important, potentially hazardous interactions with: amprenavir, aprepitant, beclomethasone, buprenorphine, calcium, chloramphenicol, cimetidine, clobazam, clorazepate, cyclosporine, cyproterone, darunavir, dasatinib, delavirdine, dexamethasone, diazoxide, disulfiram, dopamine, fesoterodine, fluconazole, flunisolide, fluoxetine, fosamprenavir, ginkgo biloba, hydrocortisone, imatinib, indinavir, influenza vaccines, isoniazid, isradipine, itraconazole, lacosamide, lapatinib, lopinavir, meperidine, methylprednisolone, midazolam, mivacurium, nelfinavir, nilotinib, nilutamide, phenylbutazone, piracetam, posaconazole, prednisolone, prednisone, primrose, ritonavir, rivaroxaban, sage, saquinavir, solifenacin, St John’s wort, sucralfate, telithromycin, temsirolimus, teniposide, ticlopidine, tizanidine, tolvaptan, triamcinolone, uracil/tegafur, vigabatrin
