ABSTRACT

Synonym: CC1-779 Trade name: Torisel (Wyeth) Indications: Renal cell carcinoma, other cancers Category: Analog of sirolimus; mTOR inhibitor Half-life: 13-25 Hours Clinically important, potentially hazardous interactions with: atazanavir, carbamazepine, clarithromycin, dexamethasone, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, phenobarbital, phenytoin, rifabutin, rifampicin, rifampin, ritonavir, saquinavir, St John’s wort, telithromycin, voriconazole