ABSTRACT
As noted in prior chapters, toxicants vary greatly in their potency, target organ, and mode of action. To provide proper orientation for additional in-depth targeted studies, conventional toxicity studies are generally carried out fi rst. These studies are designed to provide indications of the appropriate dosage range, the probable adverse effect, and the target organ (e.g., liver), system (e.g., respiratory), or special toxicity (e.g., carcinogenicity).
