ABSTRACT

Unlike the other steroid hormones, the mineralocorticoid aldosterone is not transported in plasma bound to a specific protein. Its major actions are to stimulate the exchange of sodium for protons and potassium ions across cell membranes, and to control sodium and water balance in the kidney as discussed in Topic M5. Like the corticosteroids, aldosterone is inactivated by conjugation in the liver with glucuronate or sulphate, and excreted in the urine.