ABSTRACT

Exercise 11.1 180

Previous chapters of this book have described both the general principles for stereological estimation and also the details of a number of specific techniques. In both cases we have implicitly referred either to a global quantity, such as total number of cells within a reference space, or an average size over all objects within that reference space. However, the same general approach both to sampling and use of geometrical probes can be applied to individual objects. Over recent years this approach has become known as ‘single-object’ stereology. An excellent review of the mathematical basis of single-object stereology and its relationship with classical stereology is provided by Cruz-Orive (1997).