This chapter as compared with the others is inevitably more politically sensitive for it tackles the most difficult challenge that any institution may face: the elimination of existing organs, which may be vigorously opposed from within and from the outside. Yet pruning is necessary if we wish to make the United Nations an effective and relevant system. Coordination, more politically feasible, is also essential and sometimes implies major restructuring. Nevertheless, no endeavour for reform can be meaningful without the participation and the support of Member States. Moreover, coordination in the United Nations system is also a reflection of coordination of the policies of the various Governments. This problem should not be underestimated and the blame for failure in this regard should not be placed solely on the United Nations. Governments also need to play their part. This chapter will try to set the trend by giving practical examples of realignment in some of the major areas of the United Nations.