ABSTRACT
After studying this chapter, you should be able to:
describe the effects of exercise on plasma cytokines;
discuss the evidence that interleukin(IL)-6 is secreted from contracting muscle;
describe the metabolic and immunoregulatory roles of IL-6;
describe the effects of exercise on cytokine production by leukocytes;
understand the link between chronic disease risk and chronic inflammation;
describe the effects of a sedentary lifestyle and obesity on inflammation in adipose tissue;
describe the long-term health benefits of performing regular exercise;
discuss the anti-inflammatory actions of IL-6 and IL-10;
appreciate other mechanisms by which exercise can exert anti-inflammatory effects.