ABSTRACT

Historically, immune responses have been classified by either of two well-known schemes. In one, there is the innate and the acquired response. In the other, there is the cell -mediated and humoral response categories. There is overlap between these schemes. To understand the pivotal role that the cannabinoid receptor circuit plays in modulating the immune system, and to understand potential therapeutic applications of cannabinoids, a more modern division into T-helper I (Thl) and T-helper 2 (Th2) responses must be made (see Figure 10.1).