This chapter discusses ten information governance (IG) principles that are the result of the author's research and consulting efforts, where a great deal of practical information on IG program successes, failures, and Best Practices was synthesized, analyzed, and distilled. There are also other sets of principles that apply to IG efforts and can help provide a more complete understanding of IG programs, especially early in the IG program development process. These IG principles reflect, reinforce, and expand on the previous sets. The Information Governance Principles for Healthcare® apply to all sizes of healthcare organizations, in both the private and public sectors, and can be used to establish consistent practices across business units. Principle of Least Privilege should be used to control who has access to which information, on which devices, and when. Patient privacy is a major issue in healthcare and a key aspect of IG programs. Privacy considerations should be injected into daily business processes.