ABSTRACT
Clozapine has low potency at D2 antagonism. It has a much higher potency as a D1 antagonist and has antagonist activity at muscarinic and histamine (H1) receptors. It has more action on D4 receptors than most other antipsychotics.
Clozapine has low potency at D2 antagonism. It has a much higher potency as a D1 antagonist and has antagonist activity at muscarinic and histamine (H1) receptors. It has more action on D4 receptors than most other antipsychotics.