ABSTRACT
Glycolysis is a set of reactions that takes place in the cytoplasm of prokaryotes and eukaryotes. The roles of glycolysis are to produce energy and to produce intermediates for biosynthetic pathways. Glycolysis has a dual role. The first is to generate adenosine triphosphate (ATP). Although only two ATPs per glucose are made directly from the reactions of the glycolytic pathway, it also feeds substrates into the citric acid cycle and oxidative phosphorylation, where most ATP is made. The second role is to produce intermediates that act as precursors for a number of biosynthetic pathways. The most important control step of glycolysis is the irreversible reaction catalyzed by phosphofructokinase (PFK). The enzyme is regulated in several ways: ATP/AMP, Citrate, Fructose 2,6-bisphosphate and H+ions. Glycolysis is a series of reactions that takes place in the cytoplasm of all prokaryotes and eukaryotes. Glycolysis converts one molecule of glucose into two molecules of pyruvate.
