In this chapter, we look at the evolution of work as people and artificially intelligent machines deepen collaborative relationships. We consider AI not a replacement to human workers, but an enabling layer that is complementary to uniquely human skills. If we can successfully manage the human-machine interface, human learning and performance will be significantly amplified. Leveraging our relationship with AI requires us to place trust in technology. We consider the potential risk of atrophy resulting from an ongoing reliance on machines to perform work previously requiring certain human skills.