A cortisoaked brain is the extreme end of the continuum and represents the most dangerous threat. This is a brain that truly believes risk to safety is imminent and all efforts need to be made to preserve life. In a cortisoaked brain, the hippocampus is essentially off-line. It is not able to do its job of helping various brain areas coordinate and work together. While the hippocampus becomes less responsive, the amygdala steps up and takes over. The amygdala continues to thrive when the situation is consistently read as threatening. The decreased engagement of the prefrontal cortex also means that the amygdala is getting no message to calm down. This absence of oversight allows the amygdala to continue facilitating cortisol production, maintaining emergency status. The ability to think clearly and logically is significantly disrupted in a cortisoaked brain. Shame and guilt are common experiences for those who have been or are cortisoaked.