This final chapter reflects on the paths and ways to overcome intellectual monopoly capitalism. At the global level, we argue that a new (common) knowledge regime should be created, which also requires to change the now prevailing academic culture that reinforces knowledge assetization. Transformations must be globally coordinated; thus, new institutions ought to be put in place. Another dimension refers to innovation policies for structural change in the peripheries. Non-core states should limit all forms of extractivism and heavily invest in planning new production and innovation networks. Global agreements should be put in place to strengthen labour market regulation forbidding new and old forms of informality. Finally, to counterbalance intellectual monopoly capitalism, grassroots social movements and workers’ unions play a key role. The chapter ends with a special call for action addressed to social scientists and scientists in general.