This chapter presents several case studies. The first case study describes the importance of the physical environment and how two leaders planned and implemented changes within their public school building to reduce stress and trauma for the staff and the clients they serve. The next case describes how a site supervisor working within a large urban school district is creating a trauma-responsive and healing centered environment for children, staff and families within a preK. This is followed by a case example that highlight trauma-responsive family engagement in an early learning center. A preschool teacher describes how learning about trauma changed her work with children and families and the different ways her agency supports her. The next case study describes a community collaborative implementing the Trauma-Responsive Environments Everywhere or TREE Project. The coordinator for a 0–8 mental health collaborative describes how she worked collaboratively with many community members to bring the TREE project to their county. The final case study is in a hospital setting where a Certified Child Life Specialist describes how he works with his colleagues to create a trauma-responsive approach in his work with children who are hospitalized and their families.