There’s much in the press about how difficult it is for women to make work work around day-to-day life. Women tend to take the lion’s share of the domestic housework and be the primary carers of children and ageing parents. In this chapter, the authors look at how their female entrepreneurs make their work work around their lives, including the importance of: really wanting it and being prepared to make sacrifices, having a supportive partner, getting the family involved and managing guilt, and creating balance. Having a supportive home partner was widely cited as significantly helpful when starting out. Many of our female entrepreneurs appreciated the support of their home partner in helping to shoulder the burden and sacrifices that they needed to make during the start-up phase, as well as to share the childcare. There is much in the press about how difficult it is to be a successful businesswoman and a great mother.