There comes a time in all entrepreneurial businesses when the start-up phase is over. Female entrepreneurs need to decide if they want to scale up and, if so, whether they have the necessary capabilities to do so. In this chapter, the authors explain start-up phase to look at some of the qualities that it takes to scale up a successful business. Notably the leadership qualities required to grow a business, changing female entrepreneurs and others’ roles as the business grows, taking their business to the next stage, staying true to their entrepreneurial roots, and managing the end game. The authors look at some of these, including: building a more well-rounded leadership style, and treating female entrepreneurs' people and those with whom they do business with respect. Victoria Mellor, founder of Melcrum, went to business school eight years after starting her business because she realised that she lacked the financial and planning skills to scale her business.