ABSTRACT

This chapter provides an insider's view of the molecular revolution in anthropology. Beginning in 1959, Morris Goodman had been generating a large body of data from comparisons of various primate serum proteins. Both Goodman and Emile Zuckerkandl presented papers, but nobody could get beyond the fact that use of the term "rate" meant that two variables, amount of change and amount of time, had to be measured, and the only way to get amount of time was directly from the fossil record. By 1963, however, Morris Goodman at Wayne State University in Detroit, Emile Zuckerkandl and Linus Pauling at Stanford, and Emmaneul Margoliash and Emil Smith at Armour Labs in Chicago had given us the bits and pieces of a new approach. In 1961, Zuckerkanul and Pauling, working with some very fragmentary hemoglobin data, had suggested that genes and proteins appeared to have accumulated mutational change in a clocklike fashion.