ABSTRACT
This chapter will explore the origins, course, and consequences of antipsychotic-induced parkinsonism and tardive dyskinesia. While the advent of second-generation antipsychotics has diminished the impact of these neurological disorders, they remain clinically important and a source of suffering to those taking antipsychotics. Indeed, they are a major part of present-day media commercials featuring antipsychotics. This discussion will also emphasize the ambivalence demonstrated by the drug industry and academia as they struggle to explain these drug-induced abnormalities in motor functioning and their associated effects, including impairment of cognitive functioning and quality of life. A description of several new and more effective treatments for tardive dyskinesia will be included, as well as a brief discussion of genetic influences.
