This chapter explains the operationalization of the aforementioned Eastern systems theories into an applicable methodology of sustainable value creation for organizations and entrepreneurs that aims to generate positive impact. This model is called Zen Business, a model I created in 2013 after years of experience and research in Asia. This method guides, for the first time, the systemic application of the symbiotic relationship between Taoism and Buddhism to sustainable management. The chapter explains the Zen Business methodology and tools in detail: the five corporate stars (Human Leadership, Stakeholders, Marketing and Innovation, Full Profit, Brand Impact Recognition); the dynamics of transformation (system diagnosis, value generation and control cycles); the five organizational archetypes; and the Zen Business wheel for sustainable business model design.