This chapter reviews a closed-ended support group run Massachusetts General Hospital (MGH). It reviews the topics and structure of the group. It also has the element of evaluation and critique of the pros and cons of developing a closed-ended group. It evaluates each session and the positives and negatives of running this type of group with considering the hospital and local community resources. The chapter also expands on elements of the specific topics planned and then the topics discussed. It reviews the flexibility that comes with developing a group and overviews the benefits of a close-ended support group. By reading this chapter, social workers and oncology providers can begin to develop their own group based on the experience at MGH.