This chapter is an overview of the tandem hybrid social enterprise. Tandem means “a relationship between two persons or things involving cooperative action and mutual dependence.” The two components of the tandem hybrid are a for-profit entity and a non-profit entity that are structurally linked and working together in mutual dependence to achieve a social mission. The tandem hybrid model is illustrated by two organizations started by social entrepreneur Scott Boyer, OWP Pharmaceuticals and the ROW Foundation. This chapter shows how the tandem hybrid is similar to, but different from, other social enterprises. It briefly explains the four distinctives of the tandem hybrid. It is a social enterprise: driven by a compelling social mission; financed by commercial success; structured to retain control, and scalable and sustainable for the long haul. Throughout the chapter, Scott shares his experience creating and launching his tandem hybrid in segments called “Scott’s Story.”