ABSTRACT

Since 1953, when James Watson and Francis Crick first determined the structure of the DNA molecule, scientists have learned a great deal about the human genome and its role in human development. Much of this progress has been made possible by the adoption of a particular conception of our genetic machinery, known as the 'central dogma'. The central dogma states that information flows in one direction only: from Dioxi-ribonucleic-acid, to ribonucleic-acid, to protein. The central dogma, while useful in the laboratory, does not provide an adequate explanation of the role of the genes in real-life development. DNA provides a blueprint from which living creatures are constructed; however, communication between the molecules involved in that construction resembles a richly interconnected network, rather than the linear chain of command implied by the central dogma.