ABSTRACT
Introduction Although transplantation is accepted as the best available therapy for people with end stage renal failure, it is unfortunate that not all patients are suitable candidates. Despite the many advances that have occurred over recent years, the secrets of tissue typing have not been fully unravelled. This means that many patients wait for extended periods of time before being offered a transplant. For those who do have a transplant, nonspecific immunosuppression and tissue incompatibility can result in rejection. Technical mishaps can cause the transplant to become necrotic and require removal. Despite these difficulties, transplantation is a viable option and optimum preparation affords the best opportunity for success, despite the uncertainties.
